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金属组学与人体健康；仪器分析在公共卫生领域中的应用

1. 中华人民共和国科学技术部，典型新兴农用化学品的暴露特征及其生殖健康风险评估，科技部政府间国际科技创新合作（中国和美国），2022YFE0134900，2023-01 至 2025-12，200万元，在研，骨干

2. 国家自然科学基金-地区科学基金项目，82060600，白云鄂博矿区轻稀土暴露与小于胎龄儿的相关性研究，2021-01至2024-12，进行中，作为合作单位（负责经费20.1万）

2. 北京大学医学交叉种子基金，BMU2017MX006，基于血浆金属组学和氨基酸代谢组学的首发精神分裂症研究，2018/01-2018/12，已结题，主持

3. ju11net九州体育青年人才计划，金属元素与神经管畸形发生风险的病例对照研究，2016/12-2018/12，已结题，主持

4. 北京市自然科学基金面上项目，2122051，无机指纹与常见致病菌快速检定，2012/01-2014/12，11万元，已结题，参加

5. 国家自然科学基金面上项目，30972434，“同体血、尿、发、脏器铅指纹差异现象”成因研究，2010/01-2012/12，30万元，已结题，参加

1. Lailai Yan#, Juntuo Zhou#, Dong fang Wang，Dan dan Si，Ya qiong Liu，Li jun Zhong* Yuxin Yin*. Unbiased lipidomic profiling reveals metabolomic changes during the onset and antipsychotics treatment of schizophrenia disease, Metabolomics, 2018, 14(80): 80.

2. Lailai Yan#, Bin Wang#, Zhenjiang Li, Yaqiong Liu, Wenhua Huo, Jingyu Wang*, Zhiwen Li*, Aiguo Ren, Association of essential trace metals in maternal hair with the risk of neural tube defects in offspring, Birth Defects Research A, 2017, 109(3): 234-243.

3. Mengyuan Ren#, Lailai Yan#, Yiming Pang, Xiaoqian Jia, Jing Huang , Guofeng Shen, Hefa Cheng, Xilong Wang, Bo Pan, Zhiwen Li, Bin Wang. External interference from ambient air pollution on using hair metal(loid)s for biomarker-based exposure assessment. Environment International, 2020, 137, 105584.

4. Xiangrong Xu# , Yuanyuan Wang#, Na Han, Xiangming Yang, Yuelong Ji, Jue Liu, Chuyao Jin , Lizi Lin , Shuang Zhou, Shusheng Luo, Heling Bao, Zheng Liu, Bin Wang, Lailai Yan*, Hai-Jun Wang* and Xu Ma*. Early Pregnancy Exposure to Rare Earth Elements and Risk of Gestational Diabetes Mellitus: A Nested Case-Control Study. Frontiers in Endocrinology, 2021, 12: 774142.

5. Minghao Wang#, Lailai Yan#, Siqi Dou#, Liu Yang, Yiwen Zhang, Wenzhong Huang, Shanshan Li, Peng Lu*, Yuming Guo*, Blood multiple heavy metals exposure and lung function in young adults: A prospective Cohort study in China, Journal of Hazardous Materials, 2023, 459, 132064.

6. Yongxiu Hao#, Lailai Yan#, Yiming Pang, Huina Yan, Le Zhang, Jufen Liu, Nan Li, Bin Wang, Yali Zhang* , Zhiwen Li, Rongwei Ye, Aiguo Ren. Maternal serum level of manganese, single nucleotide polymorphisms, and risk of spontaneous preterm birth: A nested case-control study in China. Environmental Pollution, 2020, 262, 114187.

7. Bing Cao#*, Ruiqi Wang#, Angela T.H. Kwan, Roger S. McIntyre, Lailai Yan * Association between rare earth elements and depression: Evidence from pilot mice model of chronic unpredictable mild stress-induced depression and human studies of major depressive disorder, Chemosphere, 2023, 345: 140525.

8. Huang, N#, Cao, B#, Brietzke, E, Park, C, Cha, D, Pan, Z, Zhu, J, Liu, Y, Xie, Q, Zeng, J, McIntyre, R S, Wang, J*, Yan, L*. A pilot case-control study on the association between N-acetyl derivatives in serum and first-episode schizophrenia. Psychiatry Res, 2019, 272, 36-41.

9. Yiming Pang, Yunhe Guo, Kexin Li, Mengyuan Ren, Xiaoqian Jia, Zewu Li, Bin Wang*, Lailai Yan*, Zhiwen Li. Potential effect of germanium exposure on the risk of influenza-like illness in housewives in Shanxi Province, China. Science of the Total Environment, 2019, 682, 208-212. 

10. Yi Bai, Changmao Long, Guiping Hu, Di Zhou, Xiaoying Gao , Zhangjian Chen , Tiancheng Wang, Shanfa Yu , Youli Han*, Lailai Yan*. Environ Toxicol Pharmacol, 2019, 72: 103237.